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. 2021 Sep;37(9):2799-2806.
doi: 10.1007/s00381-021-05201-z. Epub 2021 May 10.

Neurodevelopmental profile in children with benign external hydrocephalus syndrome. A pilot cohort study

Federica Maruccia  1   2 , Laura Gomáriz  3 , Katiuska Rosas  4 , Turgut Durduran  5   6 , Fernando Paredes-Carmona  7 , Juan Sahuquillo #  3   4   8 , Maria A Poca #  3   4   8
Affiliations

Neurodevelopmental profile in children with benign external hydrocephalus syndrome. A pilot cohort study

Federica Maruccia et al. Childs Nerv Syst. 2021 Sep.

Abstract

Purpose: The management of children with benign external hydrocephalus (BEH) remains controversial. Most BEH children do well in the long-term, but a substantial number have temporary or permanent psychomotor delays. The study aims to assess the prevalence and pattern of neurodevelopmental delay in a cohort of children with BEH.

Methods: We conducted a cohort study of 42 BEH children (30 boys and 12 girls, aged 6 to 38 months). A pediatric neurosurgeon performed a first clinical evaluation to confirm/reject the diagnosis according to the clinical features and neuroimaging studies. Two trained evaluators assessed the child's psychomotor development using the third edition of the Bayley Scales of Infant and Toddler Development (Bayley-III). Developmental delay was defined as a scaled score < 7 according to the simple scale and/or a composite score < 85.

Results: Eighteen children (43%) presented statistically lower scores in the gross motor and composite motor of the Bayley-III scales compared to their healthy peers.

Conclusion: In BEH, it is important to establish a diagnostic algorithm that helps to discriminate BEH patients that have self-limiting delays from those at risk of a persistent delay that should be referred for additional studies and/or interventions that might improve the natural evolution of a disease with high impact on the children and adult's quality of life.

Keywords: Bayley III scales; Child development; Macrocephaly; Psychomotor assessment.

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