Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021:1318:81-90.
doi: 10.1007/978-3-030-63761-3_5.

The Incubation Period of COVID-19: Current Understanding and Modeling Technique

Affiliations
Review

The Incubation Period of COVID-19: Current Understanding and Modeling Technique

Char Leung. Adv Exp Med Biol. 2021.

Abstract

This chapter aims to answer the following questions regarding the incubation period of COVID-19. Why is understanding the incubation period of COVID-19 important? How long is the incubation time, and what are the associating factors? How should the incubation period be modeled given the current pandemic situation? Where should we go from here? As a critical epidemiological metric, the incubation period is of public health and clinical importance. While the incubation time of COVID-19 is generally similar to that of SARS and MERS, recent studies identifying factors that impact the incubation period of COVID-19, travel history, for example, only tell part of the story. Therefore, in addition to reviewing current findings, this chapter also explores the modeling technique and future research directions of the incubation period of COVID-19.

Keywords: COVID-19; Epidemiology; Incubation period; MERS; Modeling; SARS.

PubMed Disclaimer

References

    1. Armenian HK, Lilienfeld AM (1983) Incubation period of disease. Epidemiol Rev 5:1–15. https://doi.org/10.1093/oxfordjournals.epirev.a036254 - DOI - PubMed
    1. Assiri A, McGeer A, Perl TM, Price CS, Al Rabeeah AA, Cummings DA, Alabdullatif ZN, Assad M, Almulhim A, Makhdoom H, Madani H, Alhakeem R, Al-Tawfiq JA, Cotten M, Watson SJ, Kellam P, Zumla AI, Memish ZA, Team KM-CI (2013) Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med 369(5):407–416. https://doi.org/10.1056/NEJMoa1306742 - DOI - PubMed - PMC
    1. Awofisayo-Okuyelu A, Hall I, Adak G, Hawker JI, Abbott S, McCARTHY N (2017) A systematic review and meta-analysis on the incubation period of Campylobacteriosis. Epidemiol Infect 145(11):2241–2253. https://doi.org/10.1017/S0950268817001303 - DOI - PubMed
    1. Backer JA, Klinkenberg D, Wallinga J (2020) Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20–28 January 2020. Euro Surveill 25(5). https://doi.org/10.2807/1560-7917.ES.2020.25.5.2000062
    1. Cai QC, Xu QF, Xu JM, Guo Q, Cheng X, Zhao GM, Sun QW, Lu J, Jiang QW (2006) Refined estimate of the incubation period of severe acute respiratory syndrome and related influencing factors. Am J Epidemiol 163(3):211–216. https://doi.org/10.1093/aje/kwj034 - DOI - PubMed

LinkOut - more resources