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Comment
. 2021 Jul 28;144(6):1629-1631.
doi: 10.1093/brain/awab168.

On the intersection between systemic infection, brain vascular dysfunction and dementia

Mikko T Huuskonen  1   2 , Kassandra Kisler  1   2 , Abhay P Sagare  1   2 , Berislav V Zlokovic  1   2
Affiliations
Comment

On the intersection between systemic infection, brain vascular dysfunction and dementia

Mikko T Huuskonen et al. Brain. .

Abstract

This scientific commentary refers to ‘Systemic infection exacerbates cerebrovascular dysfunction in Alzheimer’s disease’ by Asby et al. (doi:10.1093/brain/awab094).

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Figures

Figure 1
Figure 1
Common features of cerebrovascular dysfunction in vascular dementia and Alzheimer’s disease. Both vascular dementia (VaD) and Alzheimer’s disease (AD) share markers of cerebrovascular dysfunction and elevated cytokines that are further exacerbated by systemic infection (SI), as shown by Asby et al. Other factors can also influence or aggravate elevation of these markers.
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References

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