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Editorial
. 2021 May;17(5):265-271.
doi: 10.1200/OP.21.00001.

Participation of Black Americans in Cancer Clinical Trials: Current Challenges and Proposed Solutions

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Editorial

Participation of Black Americans in Cancer Clinical Trials: Current Challenges and Proposed Solutions

Muhammad Awidi et al. JCO Oncol Pract. 2021 May.

Abstract

Low participation of Black Americans in cancer clinical trials is a well-established predicament. Many factors resulted in this current dilemma with racism being the fundamental unit. Here, we discuss some current challenges and proposed solutions to help in increasing the enrollment of Black Americans in cancer clinical trials. We suggest implementing the least acceptable race-specific percentage as a new bar that registrational clinical trials need to pass before cancer drugs approval. Clinical trials will continue to draw the future of cancer therapeutics in which we believe that a prompt improvement of Black Americans participation is warranted.

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Figures

FIG 1.
FIG 1.
A proposed implementation plan of the least acceptable race-specific percentage.

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References

    1. Bleyer A, Montello M, Budd T, et al. : National survival trends of young adults with sarcoma: Lack of progress is associated with lack of clinical trial participation. Cancer 103:1891-1897, 2005 - PubMed
    1. Green AK, Curry M, Trivedi N, et al. : Assessment of outcomes associated with the use of newly approved oncology drugs in Medicare beneficiaries. JAMA Netw Open 4:e210030, 2021 - PMC - PubMed
    1. Conforti F, Pala L, Bagnardi V, et al. : Cancer immunotherapy efficacy and patients' sex: A systematic review and meta-analysis. Lancet Oncol 19:737-746, 2018 - PubMed
    1. DeSantis CE, Miller KD, Goding Sauer A, et al. : Cancer statistics for African Americans, 2019. CA Cancer J Clin 69:211-233, 2019 - PubMed
    1. Siegel RL, Miller KD, Jemal A: Cancer statistics, 2020. CA Cancer J Clin 70:7-30, 2020 - PubMed

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