Participation of Black Americans in Cancer Clinical Trials: Current Challenges and Proposed Solutions
- PMID: 33974816
- PMCID: PMC8258017
- DOI: 10.1200/OP.21.00001
Participation of Black Americans in Cancer Clinical Trials: Current Challenges and Proposed Solutions
Abstract
Low participation of Black Americans in cancer clinical trials is a well-established predicament. Many factors resulted in this current dilemma with racism being the fundamental unit. Here, we discuss some current challenges and proposed solutions to help in increasing the enrollment of Black Americans in cancer clinical trials. We suggest implementing the least acceptable race-specific percentage as a new bar that registrational clinical trials need to pass before cancer drugs approval. Clinical trials will continue to draw the future of cancer therapeutics in which we believe that a prompt improvement of Black Americans participation is warranted.
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References
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- Bleyer A, Montello M, Budd T, et al. : National survival trends of young adults with sarcoma: Lack of progress is associated with lack of clinical trial participation. Cancer 103:1891-1897, 2005 - PubMed
-
- Conforti F, Pala L, Bagnardi V, et al. : Cancer immunotherapy efficacy and patients' sex: A systematic review and meta-analysis. Lancet Oncol 19:737-746, 2018 - PubMed
-
- DeSantis CE, Miller KD, Goding Sauer A, et al. : Cancer statistics for African Americans, 2019. CA Cancer J Clin 69:211-233, 2019 - PubMed
-
- Siegel RL, Miller KD, Jemal A: Cancer statistics, 2020. CA Cancer J Clin 70:7-30, 2020 - PubMed
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