Muscle VPS39 deficiency in people with T2DM

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Comment

Shimona Starling. Nat Rev Endocrinol. 2021 Jul.

. 2021 Jul;17(7):383.

doi: 10.1038/s41574-021-00508-y.

No abstract available

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VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics.
Davegårdh C, Säll J, Benrick A, Broholm C, Volkov P, Perfilyev A, Henriksen TI, Wu Y, Hjort L, Brøns C, Hansson O, Pedersen M, Würthner JU, Pfeffer K, Nilsson E, Vaag A, Stener-Victorin E, Pircs K, Scheele C, Ling C. Davegårdh C, et al. Nat Commun. 2021 Apr 23;12(1):2431. doi: 10.1038/s41467-021-22068-5. Nat Commun. 2021. PMID: 33893273 Free PMC article.

1. Davegårdh, C. et al. VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics. Nat. Commun. 12, 2431 (2021) - DOI