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Review
. 2021 May 3:14:1647-1659.
doi: 10.2147/IJGM.S298705. eCollection 2021.

Facing Cell Autophagy in Gastric Cancer - What Do We Know so Far?

Ting Xiu  1   2 , Qie Guo  1 , Fan-Bo Jing  1
Affiliations
Review

Facing Cell Autophagy in Gastric Cancer - What Do We Know so Far?

Ting Xiu et al. Int J Gen Med. .

Abstract

Autophagy is a process by which misfolded proteins and damaged organelles in the lysosomes of tumor cells were degraded reusing decomposed substances and avoiding accumulation of large amounts of harmful substances. Here, the role of autophagy in the development of malignant transformation of gastric tumors, and the underlying mechanisms involved in autophagy formation, and the application of targeted autophagy in the treatment of gastric cancer were summarized.

Keywords: autophagy; autophagy-related genes; gastric cancer; lysosomes; targeted therapy.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

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