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Review
. 2021 Apr 22:10:310.
doi: 10.12688/f1000research.52031.1. eCollection 2021.

Optical coherence tomography's current clinical medical and dental applications: a review

Saqib Ali  1 , Saqlain Bin Syed Gilani  2 , Juzer Shabbir  3 , Khalid S Almulhim  4 , Amr Bugshan  1 , Imran Farooq  5
Affiliations
Review

Optical coherence tomography's current clinical medical and dental applications: a review

Saqib Ali et al. F1000Res. .

Abstract

Optical coherence tomography (OCT) is a non-invasive investigative technique that is used to obtain high-resolution three-dimensional (3D) images of biological structures. This method is useful in diagnosing diseases of specific organs like the eye, where a direct biopsy cannot be conducted. Since its inception, significant advancements have been made in its technology. Apart from its initial application in ophthalmology for retinal imaging, substantial technological innovations in OCT brought by the research community have enabled its utilization beyond its original scope and allowed its application in many new clinical areas. This review presents a summary of the clinical applications of OCT in the field of medicine (ophthalmology, cardiology, otology, and dermatology) and dentistry (tissue imaging, detection of caries, analysis of dental polymer composite restorations, imaging of root canals, and diagnosis of oral cancer). In addition, potential advantages and disadvantages of OCT are also discussed.

Keywords: Dentistry; Imaging; Medicine; OCT; Optical coherence tomography.

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Conflict of interest statement

No competing interests were disclosed.

References

    1. Podoleanu AG: Optical coherence tomography. J. Microsc. 2012;247(3):209–219. 10.1111/j.1365-2818.2012.03619.x - DOI - PMC - PubMed
    1. Ibne MM: Optical Coherence Tomography: Basic Concepts and Applications in Neuroscience Research. J Med Eng. 2017;2017:3409327. 10.1155/2017/3409327 - DOI - PMC - PubMed
    1. Gurreri A, Pazzaglia A: Diabetic Macular Edema: State of Art and Intraocular Pharmacological Approaches. Adv Exp Med Biol. 2021;1307:375–389. 10.1007/5584_2020_535 - DOI - PubMed
    1. Khamar P, Rao K, Wadia K, et al. : Advanced epithelial mapping for refractive surgery. Indian J Ophthalmol. 2020;68(12):2819–2830. 10.4103/ijo.IJO_2399_20 - DOI - PMC - PubMed
    1. Maldonado RS, Mettu P, El-Dairi M, et al. : The application of optical coherence tomography in neurologic diseases. Neurol Clin Pract. 2015;5(5):460–469. 10.1212/CPJ.0000000000000187 - DOI - PMC - PubMed