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. 2022 Aug;23(5):556-561.
doi: 10.1111/pedi.13231. Epub 2021 May 18.

Incidence and clinical characteristics of pediatric-onset type 2 diabetes in Hong Kong: The Hong Kong childhood diabetes registry 2008 to 2017

Joanna Yuet-Ling Tung  1   2 , Elaine Yin-Wah Kwan  3 , Betty Wai-Man But  4 , Wilfred Hing-Sang Wong  1 , Antony Chun-Cheung Fu  5 , Gloria Pang  2   5 , Jennifer Wing-Yan Tsang  6 , Ho-Chung Yau  6 , Kiran Belaramani  2   7 , Lap-Ming Wong  7 , Shirley Man-Yee Wong  4 , Priscilla Lo  8 , Kwok-Leung Ng  8 , Wilson Kwan-Yee Yeung  3 , Kwong-Tat Chan  3 , Angela Mo-Kit Chan  9 , Sammy Wai-Chun Wong  9 , Ming-Kut Tay  10 , Jacky Chung  11 , Ching-Yin Lee  11 , Yuen-Yu Lam  12 , Pik-To Cheung  1   13
Affiliations

Incidence and clinical characteristics of pediatric-onset type 2 diabetes in Hong Kong: The Hong Kong childhood diabetes registry 2008 to 2017

Joanna Yuet-Ling Tung et al. Pediatr Diabetes. 2022 Aug.

Abstract

Objective: With increasing prevalence of childhood obesity worldwide, the incidence of pediatric-onset type 2 diabetes (T2D) is also increasing in many countries. We aim to analyze the time trend and incidence of T2D in children in Hong Kong from 2008 to 2017, and to characterize clinical characteristics at diagnosis.

Methods: Data were retrieved from the Hong Kong Childhood Diabetes Registry. All children with T2D diagnosed at the age of less than 18 years from January 1, 2008 to December 31, 2017 and managed in the public health care system were included in this study.

Results: In the incident years of 2008-2017 period, 391 children were diagnosed with T2D. The crude incidence rate was 3.42 per 100,000 persons/year [95% confidence interval (CI) 3.08-3.76], which was much higher than that in last registry of 1.27 per 100,000 persons/year in 1997-2007 (P < 0.001).Most children (76%) were asymptomatic and were diagnosed by routine screening. At presentation, a significant proportion presented with co-morbidities including fatty liver (37.9%), dyslipidaemia (35.3%), hypertension (22.5%), and microalbuminuria (12.8%).

Conclusions: The incidence of T2D in children has increased significantly in Hong Kong. Most of them were asymptomatic and picked up on routine health screening. Yet, comorbidities were commonly identified at diagnosis.

Keywords: Hong Kong; childhood diabetes registry; epidemiology; incidence; pediatrics; type 2 diabetes mellitus.

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References

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