Key characteristics of carcinogens
- PMID: 33979084
- Bookshelf ID: NBK570335
Key characteristics of carcinogens
© International Agency for Research on Cancer, 2019. For more information contact publications@iarc.fr.
Sections
- Introduction
- Characteristic 1: Is electrophilic or can be metabolically activated to electrophiles
- Characteristic 2: Is genotoxic
- Characteristic 3: Alters DNA repair or causes genomic instability
- Characteristic 4: Induces epigenetic alterations
- Characteristic 5: Induces oxidative stress
- Characteristic 6: Induces chronic inflammation
- Characteristic 7: Is immunosuppressive
- Characteristic 8: Modulates receptor-mediated effects
- Characteristic 9: Causes immortalization
- Characteristic 10: Alters cell proliferation, cell death, or nutrient supply
- Multiple mechanisms of action of human carcinogens
- Factors modulating human carcinogenesis
- References
References
Publication types
LinkOut - more resources
Full Text Sources