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. 1988;22(1):51-6.
doi: 10.1016/0022-3956(88)90028-3.

A twin study of amino acid concentrations in cerebrospinal fluid

L Hagenfeldt  1 , G Oxenstierna, G Alfredsson, G Edman, L Iselius, G Sedvall
Affiliations

A twin study of amino acid concentrations in cerebrospinal fluid

L Hagenfeldt et al. J Psychiatr Res. 1988.

Abstract

The concentrations of amino acids in the cerebrospinal fluid (CSF) were measured in pairs of healthy mono- and dizygotic twins. Intraclass correlations were calculated. Genetic and cultural heritabilities were estimated using a path analytical model. CSF levels of glycine, tyrosine and arginine were shown to be influenced by genetic factors. Genetic variation was also shown for serine, alpha-aminobutyrate and leucine. The results were compared with results from a genetic analysis of the amino acids in serum.

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