Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar 13;8(4):627-630.
doi: 10.1002/mdc3.13175. eCollection 2021 May.

Throat-Clearing Vocalizations in Primary Brain Calcification Syndromes

Eoin Mulroy  1 , Andreea Ilinca  2 , Cristina Gonzalez-Robles  1 , Francesca Magrinelli  1   3 , Andreas Puschmann  2 , Kailash P Bhatia  1
Affiliations

Throat-Clearing Vocalizations in Primary Brain Calcification Syndromes

Eoin Mulroy et al. Mov Disord Clin Pract. .
No abstract available

Keywords: calcium; language; speech; tics.

PubMed Disclaimer

Conflict of interest statement

This work was supported by the Swedish Government (ALF), Region Skåne, Skåne University Hospital, Parkinsonfonden, and The Swedish Parkinson Acadamy, all in Sweden. The authors declare that there are no conflicts of interest.

Figures

FIG. 1
FIG. 1
CT brain images of case 1 (A), his mother (B) and his son (C), and case 2 (D).
See this image and copyright information in PMC

References

    1. Batla A, Tai XY, Schottlaender L, Erro R, Balint B, Bhatia KP. Deconstructing Fahr's disease/syndrome of brain calcification in the era of new genes. Parkinsonism Relat Disord 2017;37:1–10. - PubMed
    1. Grangeon L, Wallon D, Charbonnier C, et al. Biallelic MYORG mutation carriers exhibit primary brain calcification with a distinct phenotype. Brain 2019;142(6):1573–1586. - PubMed
    1. Cen Z, Chen Y, Chen S, et al. Biallelic loss‐of‐function mutations in JAM2 cause primary familial brain calcification. Brain 2020;143(2):491–502. - PubMed
    1. Mainka T, Balint B, Gövert F, et al. The spectrum of involuntary vocalizations in humans: a video atlas. Mov Disord 2019;34(12):1774–1791. - PubMed
    1. Holstege G, Subramanian HH. Two different motor systems are needed to generate human speech. J Comp Neurol 2016;524(8):1558–1577. - PubMed

LinkOut - more resources