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. 2021 Jun;39(6):631-638.
doi: 10.1007/s40273-021-01036-3. Epub 2021 May 13.

Putting Stakeholder Engagement at the Center of Health Economic Modeling for Health Technology Assessment in the United States

Richard Z Xie  1 , Erica deFur Malik  2 , Mark T Linthicum  2 , Jennifer L Bright  2
Affiliations

Putting Stakeholder Engagement at the Center of Health Economic Modeling for Health Technology Assessment in the United States

Richard Z Xie et al. Pharmacoeconomics. 2021 Jun.

Abstract

While evidence generated from health economic (HE) models is being used more commonly in health technology assessment (HTA) in the US, it is not consistently adopted by different stakeholder groups or across therapeutic areas. We hypothesize that actively engaging with multiple stakeholder groups throughout the model development process may result in models more widely considered by decision makers. To test this hypothesis, the Innovation and Value Initiative has launched a modeling effort to build an open-source HE model focusing on the disease state 'major depressive disorder'. A 20-member advisory group has been formed with representatives from patients, employers, clinicians, innovators, payers, and researchers to guide the model development process. While this effort is still in the early stages, the ongoing stakeholder engagement effort has yielded valuable insights that inform the model design. We have also identified several challenges to implementing this new approach. Our early findings suggest that the stakeholder engagement approach to HE model development has the potential to improve HTA in the US.

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Conflict of interest statement

Richard Z. Xie, Erica deFur Malik, Mark T. Linthicum, and Jennifer L. Bright hold the positions of HEOR Manager, Director of Membership, Director of Scientific Communications, and Executive Director, respectively, at the Innovation and Value Initiative (IVI), a 501(c)(3) non-profit research organization whose members include pharmaceutical companies, patient advocacy organizations, and health systems. Richard Z. Xie was previously employed by Analysis Group, an economics consultancy with clients in the life science industry. Erica deFur Malik is the Managing Director of Malik Group, LLC, and consultant for Momentum Health Strategies. Mark. T. Linthicum was previously employed by Precision Health Economics, a health economics consultancy with clients in the life science and insurance industries. Jennifer L. Bright is also President, Momentum Health Strategies.

Figures

Fig. 1
Fig. 1
Development process for health economic models with multi-stakeholder input
See this image and copyright information in PMC

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