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Meta-Analysis
. 2021 Jul 1;139(7):717-723.
doi: 10.1001/jamaophthalmol.2021.0527.

Prevalence of Visual Acuity Loss or Blindness in the US: A Bayesian Meta-analysis

Collaborators, Affiliations
Meta-Analysis

Prevalence of Visual Acuity Loss or Blindness in the US: A Bayesian Meta-analysis

Abraham D Flaxman et al. JAMA Ophthalmol. .

Abstract

Importance: Globally, more than 250 million people live with visual acuity loss or blindness, and people in the US fear losing vision more than memory, hearing, or speech. But it appears there are no recent empirical estimates of visual acuity loss or blindness for the US.

Objective: To produce estimates of visual acuity loss and blindness by age, sex, race/ethnicity, and US state.

Data sources: Data from the American Community Survey (2017), National Health and Nutrition Examination Survey (1999-2008), and National Survey of Children's Health (2017), as well as population-based studies (2000-2013), were included.

Study selection: All relevant data from the US Centers for Disease Control and Prevention's Vision and Eye Health Surveillance System were included.

Data extraction and synthesis: The prevalence of visual acuity loss or blindness was estimated, stratified when possible by factors including US state, age group, sex, race/ethnicity, and community-dwelling or group-quarters status. Data analysis occurred from March 2018 to March 2020.

Main outcomes or measures: The prevalence of visual acuity loss (defined as a best-corrected visual acuity greater than or equal to 0.3 logMAR) and blindness (defined as a logMAR of 1.0 or greater) in the better-seeing eye.

Results: For 2017, this meta-analysis generated an estimated US prevalence of 7.08 (95% uncertainty interval, 6.32-7.89) million people living with visual acuity loss, of whom 1.08 (95% uncertainty interval, 0.82-1.30) million people were living with blindness. Of this, 1.62 (95% uncertainty interval, 1.32-1.92) million persons with visual acuity loss are younger than 40 years, and 141 000 (95% uncertainty interval, 95 000-187 000) persons with blindness are younger than 40 years.

Conclusions and relevance: This analysis of all available data with modern methods produced estimates substantially higher than those previously published.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Flaxman reported grants from NORC as a subcontract from a US Centers for Disease Control and Prevention during the conduct of the study; payments from Janssen, IHME, SwissRe, and Merck for Mothers for assistance in analysis and interpretation of licensed data previously produced by IHME; and payment from the startup Agathos Ltd for advising outside the submitted work. Dr Rein reported grants from the US Centers for Disease Control and Prevention Vision Health Initiative during the conduct of the study. No other disclosures were reported.

Figures

Figure 1.
Figure 1.. Crude Prevalence of Visual Acuity Loss or Blindness by Age for All Racial/Ethnic Groups
Increases appear starting at approximately age 60 years.
Figure 2.
Figure 2.. Age-Standardized, Sex-Standardized, and Race/Ethnicity–Standardized Visual Acuity Loss or Blindness Prevalence by State
Figure 3.
Figure 3.. Age-Standardized, Sex-Standardized, and Race/Ethnicity–Standardized Blindness Prevalence Estimates by State

Comment in

References

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