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Comment
. 2021 May 12;29(5):742-744.
doi: 10.1016/j.chom.2021.04.011.

Hair of the mouse: A skin bacteria "cocktail" gets follicles back on their feet

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Hair of the mouse: A skin bacteria "cocktail" gets follicles back on their feet

Jeanmarie R Gonzalez et al. Cell Host Microbe. .
Free article

Abstract

Microbes can boost cutaneous immune defense and skin reparative capacity. However, mechanistic understanding, especially of the latter, remains sparse. In this issue of Cell Host & Microbe, Wang et al. (2021) shed light on this, demonstrating that bacteria contribute to hair follicle neogenesis after skin wounding via keratinocyte-intrinsic IL-1R1 signaling.

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  • Bacteria induce skin regeneration via IL-1β signaling.
    Wang G, Sweren E, Liu H, Wier E, Alphonse MP, Chen R, Islam N, Li A, Xue Y, Chen J, Park S, Chen Y, Lee S, Wang Y, Wang S, Archer NK, Andrews W, Kane MA, Dare E, Reddy SK, Hu Z, Grice EA, Miller LS, Garza LA. Wang G, et al. Cell Host Microbe. 2021 May 12;29(5):777-791.e6. doi: 10.1016/j.chom.2021.03.003. Epub 2021 Apr 1. Cell Host Microbe. 2021. PMID: 33798492 Free PMC article.

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