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Comment
. 2021 May 12;29(5):744-746.
doi: 10.1016/j.chom.2021.04.010.

An NTD supersite of attack

Shee-Mei Lok  1
Affiliations
Comment

An NTD supersite of attack

Shee-Mei Lok. Cell Host Microbe. .

Abstract

To date, most antibodies recognizing the SARS-CoV-2 spike (S) protein target the receptor binding domain (RBD). Three recent studies (Cerutti et al., 2021; McCallum et al., 2021; and Suryadevara et al., 2021) report on highly protective antibodies that are specific to the N-terminal domain (NTD) and target a conserved supersite.

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Figures

Figure 1
Figure 1
SARS-CoV2 spike (S) protein and the NTD supersite (A) Schematic diagram showing the domains on the S protein. (B) Side and top views of the S protein (PDB code: 7C2L). Domains/motifs/NTD-supersite/glycosylations are colored in the same color scheme as their respective font labels.
See this image and copyright information in PMC

Comment on

References

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