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. 2022 Feb 11;74(3):525-528.
doi: 10.1093/cid/ciab436.

Evaluating the Presence of Replication-Competent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From Nursing Home Residents With Persistently Positive Reverse Transcription Polymerase Chain Reaction (RT-PCR) Results

Joseph D Lutgring  1 , Farrell A Tobolowsky  1   2 , Kelly M Hatfield  1 , Nicholas B Lehnertz  3 , Maureen M Sullivan  3 , Karen G Martin  3 , Amelia Keaton  4 , D Joseph Sexton  1 , Azaibi Tamin  1 , Jennifer L Harcourt  1 , Natalie J Thornburg  1 , Sujan C Reddy  1 , John A Jernigan  1
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Evaluating the Presence of Replication-Competent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From Nursing Home Residents With Persistently Positive Reverse Transcription Polymerase Chain Reaction (RT-PCR) Results

Joseph D Lutgring et al. Clin Infect Dis. .

Abstract

Replication-competent virus has not been detected in individuals with mild to moderate coronavirus disease 2019 (COVID-19) more than 10 days after symptom onset. It is unknown whether these findings apply to nursing home residents. Of 273 specimens collected from nursing home residents >10 days from the initial positive test, none were culture positive.

Keywords: COVID-19; RT-PCR; SARS-CoV-2; nursing home; viral culture.

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