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Randomized Controlled Trial
. 2022 Mar;9(2):1412-1422.
doi: 10.1002/nop2.917. Epub 2021 May 14.

Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models

Li Yang  1   2 , Cheng Xuan  3 , Caiyan Yu  3 , Xiaoqing Jin  1 , Pinpin Zheng  2 , Jing Yan  1
Affiliations
Randomized Controlled Trial

Effects of comprehensive intervention on life quality among the elderly with Alzheimer Disease and their caregivers based on mixed models

Li Yang et al. Nurs Open. 2022 Mar.

Abstract

Aims: We conducted a multi-sectoral comprehensive intervention for elderly Alzheimer Disease patients and their caregivers to improve their quality of life.

Design: Randomized controlled trial.

Methods: From June to June in 2019, 150 Alzheimer Disease patients were randomly selected from a nursing home in Zhejiang province of China, they were randomly divided into the intervention group and the control group. And they were given comprehensive and routine interventions respectively for six months. We used mixed models in our analyses to see how outcomes changed over time and how they were affected by the intervention, which could also solve the problems of missing values and data correlation.

Results: After six months, compared with the control group, the communication ability, housework handling ability, self-care ability and life quality of the patients in the intervention group were improved, and the quality of life and caring ability of their caregivers were also significantly improved.

Conclusion: The multi-sectoral collaborative care model proposed in this study integrated resources from several departments, effectively improved the quality of life of patients and their caregivers, and provided a way of care services for patients with Alzheimer Disease.

Impact: Multi-sectoral comprehensive intervention would improve the life quality of elderly patients with Alzheimer Disease and their caregivers.

Keywords: Alzheimer Disease; caregivers; elderly; mixed models; nursing intervention.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Flowchart of enrollment of participants in the study
See this image and copyright information in PMC

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