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Review
. 2021 Aug 9;39(8):1023-1027.
doi: 10.1016/j.ccell.2021.04.011. Epub 2021 May 13.

Interleukin-1 in tumor progression, therapy, and prevention

Cecilia Garlanda  1 , Alberto Mantovani  2
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Free article
Review

Interleukin-1 in tumor progression, therapy, and prevention

Cecilia Garlanda et al. Cancer Cell. .
Free article

Abstract

Interleukin-1 (IL-1) is a key orchestrator of inflammation and plays an important role in tumor progression. Based on preclinical models and human genetic associations, we surmise that targeting IL-1 should be considered in treating selected human tumors as well as in a prevention and/or interception setting.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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