Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 May 14;11(1):10333.
doi: 10.1038/s41598-021-89179-3.

Dementia epidemiology in Hungary based on data from neurological and psychiatric specialty services

Nóra Balázs  1 , András Ajtay  1   2 , Ferenc Oberfrank  3 , Dániel Bereczki  1   2 , Tibor Kovács  4   5
Affiliations

Dementia epidemiology in Hungary based on data from neurological and psychiatric specialty services

Nóra Balázs et al. Sci Rep. .

Abstract

Hungary has a single-payer health insurance system covering 10 million inhabitants. All medical reports of the in- and outpatient specialist services were collected in the NEUROHUN database. We used ICD-10 codes of Alzheimer's disease (AD), vascular dementia (VaD), miscellaneous dementia group and mild cognitive impairment (MCI) for the inclusion of the patients. Incidence, prevalence and survival of different dementias and MCI were calculated and analyzed depending on the diagnoses given by neurological or psychiatric services or both. Between 2011 and 2016, the mean crude incidence of all dementias was 242/100,000/year, whereas the age standardized incidence was 287/100,000/year. Crude and age standardized mean prevalence rates were 570/100,000 and 649/100,000, respectively. There were significantly more VaD diagnoses than AD, the VaD:AD ratio was 2.54:1, being the highest in patients with psychiatric diagnoses only (4.85:1) and the lowest in patients with only neurological diagnoses (1.32:1). The median survival after the first diagnosis was 3.01 years regarding all dementia cases. Compared to international estimates, the prevalence of dementia and MCI is considerably lower in Hungary and the VaD:AD ratio is reversed.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Flowchart of patient selection and the classification of subtypes of dementia (with their abbreviations) used in our study with their corresponding ICD-10 codes.
Figure 2
Figure 2
The relationship between types of dementia and MCI. MCI assigned to patients with AD, VaD, mD and all dementia diagnoses. In case of zero, the patient received MCI and another diagnosis in the same year. The date of the first diagnosis given to a patient was used for the analysis. Nr. Number.
Figure 3
Figure 3
Cases of dementias and AD between 2011 and 2016 by age groups. The bars indicate the total dementia, of which AD is highlighted with dotting.
Figure 4
Figure 4
Survival from the diagnosis of dementia subtypes plotted on a Kaplan–Meier curve, logrank test p < 0.0001.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Petersen RC. Mild cognitive impairment as a diagnostic entity. J. Intern. Med. 2004;256:183–194. doi: 10.1111/j.1365-2796.2004.01388.x. - DOI - PubMed
    1. Elahi FM, Miller BL. A clinicopathological approach to the diagnosis of dementia. Nat. Rev. Neurol. 2017;13:457–476. doi: 10.1038/nrneurol.2017.96. - DOI - PMC - PubMed
    1. Prince, M., Wimo, A.G.M., Ali, G.C., Wu, Y.T. & Prina, M. World Alzheimer Report 2015: The global impact of dementia: an analysis of prevalence, incidence, cost and trends. (Alzheimer’s Disease International, London). https://www.alzint.org/resource/world-alzheimer-report-2015/. Accessed 4 Jan 2021
    1. GBD 2016 Dementia Collaborator Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019;18:88–106. doi: 10.1016/S1474-4422(18)30403-4. - DOI - PMC - PubMed
    1. Prince M, Bryce R, Albanese E, Wimo A, Ribeiro W, Ferri CP. The global prevalence of dementia: A systematic review and metaanalysis. Alzheimers Dement. 2013;9:63–75.e2. doi: 10.1016/j.jalz.2012.11.007. - DOI - PubMed

Publication types