Deep learning in histopathology: the path to the clinic
- PMID: 33990804
- DOI: 10.1038/s41591-021-01343-4
Deep learning in histopathology: the path to the clinic
Abstract
Machine learning techniques have great potential to improve medical diagnostics, offering ways to improve accuracy, reproducibility and speed, and to ease workloads for clinicians. In the field of histopathology, deep learning algorithms have been developed that perform similarly to trained pathologists for tasks such as tumor detection and grading. However, despite these promising results, very few algorithms have reached clinical implementation, challenging the balance between hope and hype for these new techniques. This Review provides an overview of the current state of the field, as well as describing the challenges that still need to be addressed before artificial intelligence in histopathology can achieve clinical value.
Similar articles
-
Emerging role of deep learning-based artificial intelligence in tumor pathology.Cancer Commun (Lond). 2020 Apr;40(4):154-166. doi: 10.1002/cac2.12012. Epub 2020 Apr 11. Cancer Commun (Lond). 2020. PMID: 32277744 Free PMC article. Review.
-
Deep learning in cancer genomics and histopathology.Genome Med. 2024 Mar 27;16(1):44. doi: 10.1186/s13073-024-01315-6. Genome Med. 2024. PMID: 38539231 Free PMC article. Review.
-
Built to Last? Reproducibility and Reusability of Deep Learning Algorithms in Computational Pathology.Mod Pathol. 2024 Jan;37(1):100350. doi: 10.1016/j.modpat.2023.100350. Epub 2023 Oct 10. Mod Pathol. 2024. PMID: 37827448 Review.
-
Deep Learning Approaches in Histopathology.Cancers (Basel). 2022 Oct 26;14(21):5264. doi: 10.3390/cancers14215264. Cancers (Basel). 2022. PMID: 36358683 Free PMC article. Review.
-
Current status and future trends of clinical diagnoses via image-based deep learning.Theranostics. 2019 Oct 12;9(25):7556-7565. doi: 10.7150/thno.38065. eCollection 2019. Theranostics. 2019. PMID: 31695786 Free PMC article. Review.
Cited by
-
Public evidence on AI products for digital pathology.NPJ Digit Med. 2024 Oct 25;7(1):300. doi: 10.1038/s41746-024-01294-3. NPJ Digit Med. 2024. PMID: 39455883 Free PMC article.
-
Generalization of Deep Learning in Digital Pathology: Experience in Breast Cancer Metastasis Detection.Cancers (Basel). 2022 Nov 3;14(21):5424. doi: 10.3390/cancers14215424. Cancers (Basel). 2022. PMID: 36358842 Free PMC article.
-
Histology Image Viewer and Converter (HIVC): A High-Speed Freeware Software to View and Convert Whole Slide Histology Images.Comput Methods Biomech Biomed Eng Imaging Vis. 2023;11(5):1652-1660. doi: 10.1080/21681163.2023.2174776. Epub 2023 Feb 4. Comput Methods Biomech Biomed Eng Imaging Vis. 2023. PMID: 37994355 Free PMC article.
-
Artificial Intelligence in Bone Marrow Histological Diagnostics: Potential Applications and Challenges.Pathobiology. 2024;91(1):8-17. doi: 10.1159/000529701. Epub 2023 Feb 15. Pathobiology. 2024. PMID: 36791682 Free PMC article. Review.
-
Tutorial: methods for three-dimensional visualization of archival tissue material.Nat Protoc. 2021 Nov;16(11):4945-4962. doi: 10.1038/s41596-021-00611-4. Epub 2021 Oct 29. Nat Protoc. 2021. PMID: 34716449 Review.
References
-
- Hamet, P. & Tremblay, J. Artificial intelligence in medicine. Metabolism 69, S36–S40 (2017). - DOI
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical