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Case Reports
. 2021 Sep;93(9):5523-5526.
doi: 10.1002/jmv.27086. Epub 2021 May 25.

Genomic surveillance activities unveil the introduction of the SARS-CoV-2 B.1.525 variant of interest in Brazil: Case report

Felicidade Pereira  1 , Stephane Tosta  1   2 , Maricélia M Lima  3 , Luciana Reboredo de Oliveira da Silva  1 , Vanessa B Nardy  1 , Marcela K A Gómez  1 , Jaqueline G Lima  1 , Vagner Fonseca  2   4   5 , Tulio de Oliveira  5 , Jose Lourenço  6 , Luiz C Alcantara Jr  2   7 , Marta Giovanetti  2   7 , Arabela Leal  1
Affiliations
Case Reports

Genomic surveillance activities unveil the introduction of the SARS-CoV-2 B.1.525 variant of interest in Brazil: Case report

Felicidade Pereira et al. J Med Virol. 2021 Sep.

Abstract

The appearance of new variants of SARS-CoV-2 has recently challenged public health authorities with respect to tracking transmission and mitigating the impact in the evolving pandemic across countries. B.1.525 is considered a variant under investigation since it carries specific genetic signatures present in P.1, B.1.1.7, and B.1.351. Here we report genomic evidence of the first likely imported case of the SARS-CoV-2 B.1.525 variant, isolated in a traveler returning from Nigeria.

Keywords: B.1.525 variant; Brazil; SARS-CoV-2; genomic surveillance.

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Conflict of interest statement

The authors declare that there are no conflict of interests.

Figures

Figure 1
Figure 1
Genomic detection of the SARS‐CoV‐2 B.1.525 variant of interest in Bahia state, Northeast Brazil. (A) ML phylogenetic tree including the newly B.1.525 isolateobtained in this study plus n = 3852 representative SARS‐CoV‐2 strains collected up to March 21st, 2021. (C) Representation of the zoom of the B.1.525 clade. Branch support (Bootstrap and SH‐aLTR >0.9) is shown at key nodes. (D) Variant maps of the B.1.525 lineage‐defining‐mutations mapped against the SARS‐CoV‐2 genome structure. Most common mutations are highlighted. ML, maximum likelihood
See this image and copyright information in PMC

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