The effect of 1,4-diaminobutanone on the stability of ornithine decarboxylase from Aspergillus nidulans
- PMID: 339910
- PMCID: PMC1165050
- DOI: 10.1042/bj1660635
The effect of 1,4-diaminobutanone on the stability of ornithine decarboxylase from Aspergillus nidulans
Abstract
1,4-Diaminobutanone, a competitive inhibitor of ornithine decarboxylase in Aspergillus nidulans, is able to increase the half-life of this enzyme and thus stimulate an increase in its activity in vivo. It also protects ornithine decarboxylase against proteolysis by chymotrypsin in vitro.
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