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. 1977 Sep 15;166(3):635-7.
doi: 10.1042/bj1660635.

The effect of 1,4-diaminobutanone on the stability of ornithine decarboxylase from Aspergillus nidulans

The effect of 1,4-diaminobutanone on the stability of ornithine decarboxylase from Aspergillus nidulans

L Stevens et al. Biochem J. .

Abstract

1,4-Diaminobutanone, a competitive inhibitor of ornithine decarboxylase in Aspergillus nidulans, is able to increase the half-life of this enzyme and thus stimulate an increase in its activity in vivo. It also protects ornithine decarboxylase against proteolysis by chymotrypsin in vitro.

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References

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