Malnutrition, assessed by the Global Leadership Initiative on Malnutrition (GLIM) criteria but not by the mini nutritional assessment (MNA), predicts the incidence of sarcopenia over a 5-year in the SarcoPhAge cohort
- PMID: 33991331
- DOI: 10.1007/s40520-021-01880-5
Malnutrition, assessed by the Global Leadership Initiative on Malnutrition (GLIM) criteria but not by the mini nutritional assessment (MNA), predicts the incidence of sarcopenia over a 5-year in the SarcoPhAge cohort
Erratum in
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Correction to: Malnutrition, assessed by the Global Leadership Initiative on Malnutrition (GLIM) criteria but not by the mini nutritional assessment (MNA), predicts the incidence of sarcopenia over a 5-year period in the SarcoPhAge cohort.Aging Clin Exp Res. 2022 Dec;34(12):3179. doi: 10.1007/s40520-021-01901-3. Epub 2021 Jul 13. Aging Clin Exp Res. 2022. PMID: 34255298 No abstract available.
Abstract
Background: The capacity of malnutrition screening to predict the onset of sarcopenia is unknown.
Aim: Our first objective is to explore the association between the screening of malnutrition and the incidence of sarcopenia and then, to assess the added value of the diagnosis of malnutrition to predict sarcopenia over a 5-year follow-up.
Methods: Malnutrition was screened at baseline according to the MNA short-form (MNA-SF) and long-form (MNA-LF) and was diagnosed by the GLIM definition. Sarcopenia was defined using the European Working Group on Sarcopenia in Older People (EWGSOP2) criteria. Kaplan-Meier analysis and adjusted Cox regression were performed to explore the association between nutritional status and the incidence of sarcopenia.
Results: A total of 418 participants were analyzed (median age 71.7 years (67.7 - 76.8), 60% women) for our first objective. Among them, 64 (15.3%) became sarcopenic during the follow-up period. In the adjusted model, the incidence of sarcopenia was nonsignificantly associated with the risk of malnutrition for both forms of the MNA (MNA-SF: HR of 1.68 (95% CI 0.95 - 2.99); MNA-LF: HR of 1.67 (95% CI 0.86 - 3.26)). However, among the 337 participants for which a GLIM assessment was possible and in which 46 participants became sarcopenic, malnourished subjects had a higher risk than well-nourished participants of developing sarcopenia after 5 years, with an adjusted HR of 3.19 (95% CI 1.56 - 6.50).
Conclusion: A full diagnosis of malnutrition seems more useful than a simple malnutrition screening to predict the incidence of sarcopenia over 5 years.
Keywords: EWGSOP2; GLIM; MNA; Malnutrition; SarcoPhAge; Sarcopenia.
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References
-
- Landi F, Camprubi-Robles M, Bear DE et al (2019) Muscle loss: The new malnutrition challenge in clinical practice. Clin Nutr 38:2113–2120. https://doi.org/10.1016/j.clnu.2018.11.021 - DOI - PubMed
-
- Goodpaster BH, Park SW, Harris TB et al (2006) The loss of skeletal muscle strength, mass, and quality in older adults: The Health, Aging and Body Composition Study. J Gerontol Ser A Biol Sci Med Sci 61:1059–1064. https://doi.org/10.1093/gerona/61.10.1059 - DOI
-
- Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA et al (2019) Sarcopenia: Revised European consensus on definition and diagnosis. Age Ageing 48:16–31. https://doi.org/10.1093/ageing/afy169 - DOI - PubMed
-
- Shafiee G, Keshtkar A, Soltani A et al (2017) Prevalence of sarcopenia in the world: A systematic review and meta- analysis of general population studies. J Diabetes Metab Disord. https://doi.org/10.1186/s40200-017-0302-x - DOI - PubMed - PMC
-
- Mijnarends DM, Luiking YC, Halfens RJG et al (2018) Muscle, Health and Costs: A Glance at their Relationship. J Nutr Heal Aging 22:766–773. https://doi.org/10.1007/s12603-018-1058-9 - DOI
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