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. 2021 May 29;397(10289):2043-2046.
doi: 10.1016/S0140-6736(21)01115-6. Epub 2021 May 12.

Heterologous prime-boost COVID-19 vaccination: initial reactogenicity data

Robert H Shaw  1 , Arabella Stuart  1 , Melanie Greenland  1 , Xinxue Liu  1 , Jonathan S Nguyen Van-Tam  2 , Matthew D Snape  3 ; Com-COV Study Group
Affiliations

Heterologous prime-boost COVID-19 vaccination: initial reactogenicity data

Robert H Shaw et al. Lancet. .

Erratum in

  • Department of Error.
    [No authors listed] [No authors listed] Lancet. 2021 May 29;397(10289):2048. doi: 10.1016/S0140-6736(21)01156-9. Epub 2021 May 18. Lancet. 2021. PMID: 34019820 Free PMC article. No abstract available.
No abstract available

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Figures

Figure
Figure
Severity of solicited local and systemic reactions in days 0-7 after vaccination with ChAdOx1 nCoV-19 (ChAd) or BNT162b2 (BNT), by prime and boost vaccination and by vaccination group, as self-reported in participant electronic diaries ChAd/ChAd denotes a ChAd vaccine for prime and boost doses. ChAd/BNT denotes a ChAd vaccine for prime dose and a BNT vaccine for boost dose. BNT/BNT denotes a BNT vaccine for prime and boost doses. BNT/ChAd denotes a BNT for prime dose and a ChAd vaccine for boost dose. The severity presented is the participant's highest severity across 7 days after vaccination for each solicited adverse event. Fever was categorised as mild (38·0°C to <38·5°C), moderate (38·5°C to <39°C), or severe (≥39·0°C). Feverish was a self-reported feeling of feverishness. For systemic symptoms, grading was classified as mild (easily tolerated with no limitation on normal activity), moderate (some limitation of daily activity), and severe (unable to perform normal daily activity).
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