. 2021 Oct:230:276-284.

doi: 10.1016/j.ajo.2021.04.032. Epub 2021 May 13.

Importance and Severity Dependence of Physical Activity by GPS-Tracked Location in Glaucoma Patients

Jian-Yu E¹, Aleksandra Mihailovic², Catalina Garzon², Jennifer A Schrack³, Tianjing Li⁴, Sheila K West², David S Friedman⁵, Laura N Gitlin⁶, Pradeep Y Ramulu⁷

Affiliations

¹ Wilmer Eye Institute, Johns Hopkins University School of Medicine (J.-Y.E., A.M., C.G., S.K.W., P.Y.R.); Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (J.-Y.E., J.A.S., P.Y.R.).
² Wilmer Eye Institute, Johns Hopkins University School of Medicine (J.-Y.E., A.M., C.G., S.K.W., P.Y.R.).
³ Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (J.-Y.E., J.A.S., P.Y.R.); Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland (J.A.S., P.Y.R.).
⁴ Department of Ophthalmology, School of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA (T.L.).
⁵ Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts (D.S.F.).
⁶ College of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania (L.N.G.).
⁷ Wilmer Eye Institute, Johns Hopkins University School of Medicine (J.-Y.E., A.M., C.G., S.K.W., P.Y.R.); Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (J.-Y.E., J.A.S., P.Y.R.); Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland (J.A.S., P.Y.R.). Electronic address: pramulu@jhmi.edu.

PMID: 33992612
PMCID: PMC8589895
DOI: 10.1016/j.ajo.2021.04.032

Importance and Severity Dependence of Physical Activity by GPS-Tracked Location in Glaucoma Patients

Jian-Yu E et al. Am J Ophthalmol. 2021 Oct.

. 2021 Oct:230:276-284.

doi: 10.1016/j.ajo.2021.04.032. Epub 2021 May 13.

Authors

Jian-Yu E¹, Aleksandra Mihailovic², Catalina Garzon², Jennifer A Schrack³, Tianjing Li⁴, Sheila K West², David S Friedman⁵, Laura N Gitlin⁶, Pradeep Y Ramulu⁷

Affiliations

¹ Wilmer Eye Institute, Johns Hopkins University School of Medicine (J.-Y.E., A.M., C.G., S.K.W., P.Y.R.); Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (J.-Y.E., J.A.S., P.Y.R.).
² Wilmer Eye Institute, Johns Hopkins University School of Medicine (J.-Y.E., A.M., C.G., S.K.W., P.Y.R.).
³ Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (J.-Y.E., J.A.S., P.Y.R.); Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland (J.A.S., P.Y.R.).
⁴ Department of Ophthalmology, School of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA (T.L.).
⁵ Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts (D.S.F.).
⁶ College of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania (L.N.G.).
⁷ Wilmer Eye Institute, Johns Hopkins University School of Medicine (J.-Y.E., A.M., C.G., S.K.W., P.Y.R.); Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (J.-Y.E., J.A.S., P.Y.R.); Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland (J.A.S., P.Y.R.). Electronic address: pramulu@jhmi.edu.

PMID: 33992612
PMCID: PMC8589895
DOI: 10.1016/j.ajo.2021.04.032

Abstract

Purpose: To quantify the association of visual field (VF) damage on physical activity away-from-home, per away-from-home excursion, and at-home.

Design: Prospective cohort study.

Methods: Among 229 participants with glaucoma or suspected glaucoma, the severity of VF damage was defined as average sensitivity within the integrated VF (IVF). Participants wore accelerometers and global positioning system trackers for 7 days to measure physical activity and characterize activity location. Multivariable negative binomial regressions were used to test whether away-from-home activity per day, physical activity per away-from-home excursion, and at-home activity per day varied by the severity of VF damage.

Results: Each 5-dB decrement in IVF sensitivity was associated with a lower number of away-from-home activities per day (18% less moderate and vigorous physical activity [MVPA] minutes/d, 95% confidence interval, 0.69-0.97) and physical activities per away-from-home excursion (20% less MVPA minutes/excursion, 95% confidence interval, 0.65-0.98). Similar findings were noted for other away-from-home activity measures (including active minutes/steps per day, or active minutes/steps per excursion). However, worse IVF sensitivity was not associated with measures of at-home activities (MVPA minutes/d, active minutes/d, and steps/d), time spent at or away from home, or excursions/wk (P > .1 for all).

Conclusions: Restriction of physical activity in more patients with severe glaucoma results mostly from activity restriction outside the home environment. These findings highlight the importance of maintaining a safe home environment (where activity is less restricted) and increasing confidence to perform activity, particular high-intensity activity, when leaving the home amongst patients with glaucoma.

Keywords: Accelerometer, Excursion, Home Activity, GPS, Mobility, Vision Impairment, Older Adults..

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Figures

**Figure 1A.**
Away-from-home moderate & vigorous physical activity minutes per excursion and visual field damage

**Figure 1B.**
Away-from-home active minutes per excursion and visual field damage

**Figure 1C.**
Away-from-home steps per excursion and visual field damage

See this image and copyright information in PMC

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Importance and Severity Dependence of Physical Activity by GPS-Tracked Location in Glaucoma Patients

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Importance and Severity Dependence of Physical Activity by GPS-Tracked Location in Glaucoma Patients

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