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Editorial
. 2021 Sep 7;42(34):3358-3360.
doi: 10.1093/eurheartj/ehab248.

Longer sleep improves cardiovascular outcomes: time to make sleep a priority

Affiliations
Editorial

Longer sleep improves cardiovascular outcomes: time to make sleep a priority

Tamar Sofer et al. Eur Heart J. .
No abstract available

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Figures

Graphical Abstract
Graphical Abstract
Causal diagrams demonstrating potential relationships between genetic causes (G) of sleep duration, sleep duration (S), and a cardiovascular outcome (Y). (A) G is a valid instrumental variable for the relationship of S and Y, and can be used to estimated the S–Y association (orange arrow). (B) G has a pleiotropic association with Y. Because there are no unmeasured confounders (U) of the S–Y association, causal mediation analysis can be used to estimate both the direct (pleiotropic) association of G and Y, and the indirect effect via S. (C) The pleiotropic effect of G on Y can be measured by blocking the pathway through S, which is done by conditioning on levels of S. (D) The effect of S on Y independently of G can be measured by blocking pathways through G and C (measured confounders) by conditioning or using matching methods.

Comment on

References

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