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. 1977 Dec;36(6):730-42.
doi: 10.1038/bjc.1977.256.

Analysis of heteroantisera to cells from human malignant effusions by immunofluorescence and protein A binding

J P Birchall, J J Owen, B S Owen
Free PMC article

Analysis of heteroantisera to cells from human malignant effusions by immunofluorescence and protein A binding

J P Birchall et al. Br J Cancer. 1977 Dec.
Free PMC article

Abstract

Using cultured cells derived from human malignant effusions, hetero-antisera were raised in rabbits. The antisera were sequentially absorbed on various human non-tumour cells, reactivity being monitored by immunofluorescence and 125I-labelled staphylococcal protein A assays. The absorbed antisera possessed common reactivity to all tumour cells assayed. This reactivity was not histogenically determined, and our data suggest that it was not directed to oncofoetal antigens.

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