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Review
. 2021 Apr 30:12:602735.
doi: 10.3389/fendo.2021.602735. eCollection 2021.

Severity of COVID-19 and Treatment Strategy for Patient With Diabetes

Shi Jin  1 , Weina Hu  2
Affiliations
Review

Severity of COVID-19 and Treatment Strategy for Patient With Diabetes

Shi Jin et al. Front Endocrinol (Lausanne). .

Abstract

Coronavirus disease 2019 (COVID-19), which was named by the World Health Organization (WHO) in February 2020, has quickly spread to more than 200 countries around the world and was declared as a global pandemic in March 2020. The severity of the disease makes it more prone to severe symptoms and higher mortality rates in patients, especially those who are with comorbidities, including high blood pressure, cardiovascular disease, obesity, and diabetes, increases the concern over the consequences of this pandemic. However, initial reports do not clearly describe whether diabetes itself or associated comorbidities or treatment strategies contribute to the severe prognosis of COVID-19 infections. Various clinical trials are being conducted on glucose-lowering agents but to date, there is no standard treatment protocol approved for COVID-19 cases with pre-existing diabetes. This review is aimed to decipher the potential risk factors of COVID-19 involved from existing evidence. Identification of a novel therapeutic strategy could be beneficial for combating SARS-CoV-2, which might be dreadful to debilitating people who have diabetes.

Keywords: COVID-19; Diabetes mellitus; SARS-CoV-2; cytokine storm; glycemic control.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. World Health Organization . Coronavirus Disease (COVID-2019) Situation Reports (2021). Available at: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situatio....
    1. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic Characterisation and Epidemiology of 2019 Novel Coronavirus: Implications for Virus Origins and Receptor Binding. Lancet (2020) 395:565–74. 10.1016/S0140-6736(20)30251-8 - DOI - PMC - PubMed
    1. Hellewell J, Abbott S, Gimma A, Bosse NI, Jarvis CI, Russell TW, et al. Feasibility of Controlling COVID-19 Outbreaks by Isolation of Cases and Contacts. Lancet Glob Health (2020) 8:e488–96. 10.1016/S2214-109X(20)30074-7 - DOI - PMC - PubMed
    1. World Health Organization . Middle East Respiratory Syndrome Coronavirus (MERS-Cov) (2020). Available at: https://www.who.int/health-topics/middle-east-respiratory-syndrome-coron....
    1. World Health Organization . Severe Acute Respiratory Syndrome (Sars) (2020). Available at: https://www.who.int/health-topics/severe-acute-respiratory-syndrome#tab=....

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