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. 2021 Apr 21:65:102334.
doi: 10.1016/j.amsu.2021.102334. eCollection 2021 May.

Telemedicine for detecting Brugada Syndrome in eastern Indonesia: A multi-center prospective observational study

Muzakkir Amir  1 , Muhaimin Munizu  1 , Idar Mappangara  1 , Andi Tiara Salengke Adam  2
Affiliations

Telemedicine for detecting Brugada Syndrome in eastern Indonesia: A multi-center prospective observational study

Muzakkir Amir et al. Ann Med Surg (Lond). .

Abstract

Background: The incidence of Brugada syndrome has been reported to occur mostly in Asian countries. However, key countries such as Indonesia, the largest-populated Southeast Asian country, have yet to report any existing data regarding the incidence of Brugada syndrome among its population. Detecting these patients has been challenging, especially in primary healthcare settings, which generally have limited resources. Telemedicine may represent an ideal solution for initial diagnosis to determine if a patient may have this condition.

Methods: We collected and analyzed numerous 12-lead electrocardiograms (ECG) of patients who visited various healthcare centers in Makassar for routine medical check-up between June 2017-April 2018. Electrocardiograms from these centers were sent to the Cardiac Center at Dr. Wahidin Sudirohusodo Hospital in Makassar via telemedicine.

Results: During the period, we successfully obtained 9558 ECGs. While none of the patients were initially suspected of Brugada Syndrome, we found 102 (1.07%) among them to have a Brugada ECG pattern (BrEP). BrEP was more commonly found in males compared to females (67.6% vs. 32.4% of the cases found). There were significant differences in the number of confirmed cases among the types of BrEP for male and female patients. The number of confirmed cases of BrEP in male and female patients were significantly different (p < 0.05), where the number of cases for male vs. female was 8 vs. 4 for type 1, 17 vs. 1 for type 2, and 44 vs. 28 for type 3.

Conclusion: Brugada syndrome is a disease that is at grave risk of being frequently underdiagnosed. Our study indicates that telemedicine can become an appropriate tool that can assist physicians in detecting suspected patients. Future efforts should also be directed at studying the possible use of telemedicine for detecting other similarly rare conditions.

Keywords: Brugada electrocardiogram pattern; Brugada syndrome; Prevalence; Southeast Asia; Telemedicine.

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Conflict of interest statement

All of the authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Flow chart of data collection process.
Fig. 2
Fig. 2
Flow chart of research participants through the study.
Fig. 3
Fig. 3
Electrocardiogram Samples of Brugada Syndrome received using Telemedicine (a) Brugada syndrome type 1, (b) Brugada syndrome type 2, (c) Brugada syndrome type 3.
See this image and copyright information in PMC

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