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Meta-Analysis
. 2021 May 1:2021:5541613.
doi: 10.1155/2021/5541613. eCollection 2021.

Improved Overall Survival of Colorectal Cancer under Multidisciplinary Team: A Meta-Analysis

Dong Peng  1 , Yu-Xi Cheng  1 , Yong Cheng  1
Affiliations
Meta-Analysis

Improved Overall Survival of Colorectal Cancer under Multidisciplinary Team: A Meta-Analysis

Dong Peng et al. Biomed Res Int. .

Abstract

Purpose: The purpose of the current meta-analysis was to evaluate whether multidisciplinary team improved overall survival of colorectal cancer.

Methods: PubMed, EMBASE, and Cochrane Library database were searched from inception to October 25, 2020. The hazard ratio (HR) and 95% confidence (CI) of overall survival (OS) were calculated.

Results: A total of 11 studies with 30814 patients were included in this meta-analysis. After pooling the HRs, the MDT group was associated with better OS compared with the non-MDT group (HR = 0.81, 95% CI 0.69-0.94, p = 0.005). In subgroup analysis of stage IV colorectal cancer, the MDT group was associated with better OS as well (HR = 0.73, 95% CI 0.59-0.90, p = 0.004). However, in terms of postoperative mortality, no significant difference was found between MDT and non-MDT groups (OR = 0.84, 95% CI 0.44-1.61, p = 0.60).

Conclusion: MDT could improve OS of colorectal cancer patients.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of study selection.
Figure 2
Figure 2
Impact of MDT on overall survival.
Figure 3
Figure 3
Subgroup analysis of MDT on overall survival of stage IV colorectal cancer.
Figure 4
Figure 4
Postoperative mortality between MDT and non-MDT groups.
See this image and copyright information in PMC

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