Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 May 17;22(10):905.
doi: 10.1002/cphc.202100338.

Hyperpolarized 13 C Magnetic Resonance Imaging of Fumarate Metabolism by Parahydrogen-induced Polarization: A Proof-of-Concept in vivo Study

Neil J Stewart  1 , Hitomi Nakano  1 , Shuto Sugai  1 , Mitsushi Tomohiro  1 , Yuki Kase  1 , Yoshiki Uchio  1 , Toru Yamaguchi  2 , Yujirou Matsuo  2 , Tatsuya Naganuma  3 , Norihiko Takeda  4 , Ikuya Nishimura  1 , Hiroshi Hirata  1 , Takuya Hashimoto  5 , Shingo Matsumoto  1
Affiliations

Hyperpolarized 13 C Magnetic Resonance Imaging of Fumarate Metabolism by Parahydrogen-induced Polarization: A Proof-of-Concept in vivo Study

Neil J Stewart et al. Chemphyschem. .

Abstract

The front cover artwork is provided by the group of Dr. Neil J. Stewart, Prof. Hiroshi Hirata, and Dr. Shingo Matsumoto (Hokkaido University, Japan) as well as Dr. Takuya Hashimoto (Chiba University, Japan). The image shows hyperpolarized 13 C fumarate metabolism to hyperpolarized 13 C malate, which is released into the extracellular space in regions of necrotic cell death, where the cell membrane is disrupted. Read the full text of the Article at 10.1002/cphc.202001038.

PubMed Disclaimer

LinkOut - more resources