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. 2021 May;21(3):166-169.
doi: 10.7861/clinmed.2021-0243.

Nails in systemic disease

Charlotte E Gollins  1 , David de Berker  2
Affiliations

Nails in systemic disease

Charlotte E Gollins et al. Clin Med (Lond). 2021 May.

Abstract

A change in colour, size, shape or texture of finger- and toenails can be an indicator of underlying systemic disease. An appreciation of these nail signs, and an ability to interpret them when found, can help guide diagnosis and management of a general medical patient. This article discusses some common, and some more rare, nail changes associated with systemic disease.

Keywords: Beau's; clubbing; koilonychia; matrix; nail.

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Figures

Fig 1.
Fig 1.
Anatomy of the nail plate.
Fig 2.
Fig 2.
Splinter haemorrhages.
Fig 3.
Fig 3.
Mees' lines.
Fig 4.
Fig 4.
Koilonychia.
Fig 5.
Fig 5.
Yellow nail syndrome.
Fig 6.
Fig 6.
Beau's lines.
See this image and copyright information in PMC

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