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Comment
. 2021 May 17;56(10):1359-1360.
doi: 10.1016/j.devcel.2021.04.020.

Narrating the story ARC of adipose tissue aging

Sean D Kodani  1 , Yu-Hua Tseng  2
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Narrating the story ARC of adipose tissue aging

Sean D Kodani et al. Dev Cell. .
Free article

Abstract

In this issue of Developmental Cell, Nguyen et al. use scRNA-seq to explore the changing cellular landscape of subcutaneous adipose tissue during aging. In the process, they discover a new population of cells called age-dependent regulatory cells (ARC), which contributes to age-related adipose tissue dysfunction that drives metabolic disease.

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Conflict of interest statement

Declaration of interests Y.-H.T. is a consultant for Cellarity, a company which employs single-cell gene expression data to understand tissue metabolism.

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