Brazilian Protocol for Sexually Transmitted Infections, 2020: congenital syphilis and child exposed to syphilis
- PMID: 34008719
- PMCID: PMC8210493
- DOI: 10.1590/0037-8682-597-2020
Brazilian Protocol for Sexually Transmitted Infections, 2020: congenital syphilis and child exposed to syphilis
Abstract
The topics of congenital syphilis and children exposed to syphilis compose the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health in 2020. Such document was elaborated based on scientific evidence and validated in discussions with specialists. This article provides guidelines for syphilis in pregnant women and congenital syphilis clinical management, emphasizing the vertical transmission of Treponema pallidum prevention. Epidemiological and clinical aspects of these infections are presented and recommendations for managers in the programmatic and operational management of syphilis. The article also includes guidelines for health professionals in screening, diagnosing, and treating people with sexually transmitted infections and their sex partners, in addition to strategies for surveillance actions, prevention, and control of the disease. Most congenital syphilis cases arise from test failures in prenatal care or inadequate or no treatment of maternal syphilis.
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References
-
- Brasil. Ministério da Saúde . Diário Oficial da União. Brasília (DF): Oct, 2018. [2020 jul 31]. Portaria MS/SCTIE nº 42, de 5 de outubro de 2018. Torna pública a decisão de aprovar o Protocolo Clínico e Diretrizes Terapêuticas para Atenção Integral às Pessoas com Infecções Sexualmente Transmissíveis (IST), no âmbito do Sistema Único de Saúde - SUS. [Internet] Seção 1:88. Available from: http://bvsms.saude.gov.br/bvs/saudelegis/sctie/2018/prt0042_08_10_2018.html.
-
- Korenromp EL, Rowley J, Alonso M, Mello MB, Wijesooriya NS, Mahiané SG, et al. Global burden of maternal and congenital syphilis and associated adverse birth outcomes - Estimates for 2016 and progress since 2012. [2020 Jul 1];PLoS One. 2019 Feb;14(2):e0211720. doi: 10.1371/journal.pone.0211720. [internet] - DOI - PMC - PubMed
-
- Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis Sífilis - 2019. [2020 out 15];Bol Epidemiol. 2019 Oct;especial [Internet] Available from: http://www.aids.gov.br/pt-br/pub/2019/boletim-epidemiologico-sifilis-2019.
-
- Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Doenças de Condições Crônicas e Infecções Sexualmente Transmissíveis . Protocolo clínico e diretrizes terapêuticas para atenção integral às pessoas com infecções sexualmente transmissíveis (IST) Brasília: Ministério da Saúde; 2020. [2020 out 15]. [Internet] Available from: http://www.aids.gov.br/pt-br/pub/2015/protocolo-clinico-e-diretrizes-ter....
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