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. 2021 May 17;54(suppl 1):e2020605.
doi: 10.1590/0037-8682-605-2020. eCollection 2021.

Brazilian Protocol for Sexually Transmitted Infections 2020: human T-cell lymphotropic virus (HTLV) infection

Carolina Rosadas  1 , Carlos Brites  2 , Denise Arakaki-Sanchez  3 , Jorge Casseb  4 , Ricardo Ishak  5
Affiliations

Brazilian Protocol for Sexually Transmitted Infections 2020: human T-cell lymphotropic virus (HTLV) infection

Carolina Rosadas et al. Rev Soc Bras Med Trop. .

Abstract

This article addresses the Human T-lymphotropic virus (HTLV). This subject comprises the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health. HTLV-1/2 infection is a public health problem globally, and Brazil has the largest number of individuals living with the virus. HTLV-1 causes several clinical manifestations of neoplasm (adult T-cell leukemia/lymphoma) and inflammatory nature, such as HTLV-1-associated myelopathy and other manifestations such as uveitis, arthritis, and infective dermatitis. These pathologies have high morbidity and mortality and negatively impact the quality of life of infected individuals. This review includes relevant information for health authorities professionals regarding viral transmission, diagnosis, treatment, and monitoring of individuals living with HTLV-1 and 2 in Brazil. HTLV-1/2 transmission can occur through blood transfusion and derivatives, injectable drug use, organ transplantation, unprotected sexual intercourse, and vertical transmission.

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Figures

FIGURE 1:
FIGURE 1:. Classification and characteristics of adult T-cell leukemia/lymphoma.
FIGURE 2:
FIGURE 2:. Adult T-cell leukemia/lymphoma worst prognosis predictors.
FIGURE 3:
FIGURE 3:. Indications for laboratory testing for the human T-cell lymphotropic virus (HTLV-1/2).
FIGURE 4:
FIGURE 4:. Recommendations for human T-cell lymphotropic virus (HTLV-1/2) infection laboratory diagnosis.
See this image and copyright information in PMC

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