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. 2021 May 17;54(suppl 1):e2020616.
doi: 10.1590/0037-8682-616-2020. eCollection 2021.

Brazilian Protocol for Sexually Transmitted Infections 2020: acquired syphilis

Affiliations

Brazilian Protocol for Sexually Transmitted Infections 2020: acquired syphilis

Francisca Lidiane Sampaio Freitas et al. Rev Soc Bras Med Trop. .

Abstract

The Clinical Protocol and Therapeutic Guidelines for Comprehensive Care of People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health in 2020, includes updates concerning acquired syphilis. The document comprises rapid test use, safety and efficacy of benzathine benzylpenicillin, case follow-up, neurosyphilis clinical and laboratory management, approaching sex partners, assistance and monitoring of diagnosed pregnant women, and syphilis and HIV co-infection specificities, as well as a case notification summary. Health managers and professionals must be continuously trained so as to integrate care and surveillance, to strengthen actions for efficient control of syphilis, to broaden the search for sex partners, and to expand access of most vulnerable populations to health services. Most people with syphilis are asymptomatic; this contributes to the maintenance of the transmission chain. Without adequate treatment of pregnant women with syphilis, severe consequences can occur, such as miscarriage, prematurity, low birth weight, natimortality, and congenital syphilis.

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Figures

FIGURE 1:
FIGURE 1:. Acquired syphilis clinical manifestations and stages.
FIGURE 2:
FIGURE 2:. Immunological test for syphilis diagnosis.
FIGURE 3:
FIGURE 3:. Treponemal and nontreponemal test results, interpretation, and conduct.
FIGURE 4:
FIGURE 4:. Treatment and follow-up of syphilis and neurosyphilis cases.

References

    1. Brasil. Ministério da Saúde . Diário Oficial da União. Brasília (DF): Oct, 2018. [2020 out 15]. Portaria MS/SCTIE nº 42, de 5 de outubro de 2018. Torna pública a decisão de aprovar o Protocolo Clínico e Diretrizes Terapêuticas para Atenção Integral às Pessoas com Infecções Sexualmente Transmissíveis (IST), no âmbito do Sistema Único de Saúde - SUS. Seção 1:88. Available from: http://bvsms.saude.gov.br/bvs/saudelegis/sctie/2018/prt0042_08_10_2018.html.
    1. Lasagabaster MA, Guerra LO. Syphilis. [2020 Oct 15];Enferm Infecc Microbiol Clin. 2019 Jun-Jul;37(6):398–404. doi: 10.1016/j.eimc.2018.12.009. - DOI
    1. Hook EW., 3rd Syphilis. Lancet. 2017 Apr;389(10078):1550–1557. doi: 10.1016/S0140-6736(16)32411-4. Epub 2016 Dec 18. Erratum in: Lancet. 2019 Mar 9;393(10175):986. - DOI - PubMed
    1. Workowski KA, Bolan GA. Centers for Disease Control and Prevention Sexually transmitted diseases treatment guidelines, 2015. [2020 Oct 15];MMWR Recomm Rep. 2015 Jun;64(RR-03):1–137. Available from: https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6403a1.htm. - PMC - PubMed
    1. Peeling RW, Mabey D, Kamb ML, Chen X-S, Radolf JD, Benzaken AS. Syphilis. [2020 May 29];Nat Rev Dis Prim. 2017 Oct;3:17073–17073. Available from: http://www.nature.com/articles/nrdp201773. - PMC - PubMed