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. 2022 Jul 1;29(4):473-475.
doi: 10.1097/MJT.0000000000001334.

Tocilizumab-Associated Cecal Perforation in COVID-19 Pneumonia

Josephine Adunse  1 , Nithin Kesireddy, Waleed Khokher, Prabath Herath Mudiyanselage, Hyder Ali, Ragheb Assaly
Affiliations

Tocilizumab-Associated Cecal Perforation in COVID-19 Pneumonia

Josephine Adunse et al. Am J Ther. .
No abstract available

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Conflict of interest statement

The authors have no conflicts of interest to declare.

References

    1. Hart AR, Kennedy HJ, Stebbings WS, et al. How frequently do large bowel diverticula perforate? An incidence and cross-sectional study. Eur J Gastroenterol Hepatol. 2000;12:661–665.
    1. Xie F, Yun H, Bernatsky S, et al. Brief report: risk of gastrointestinal perforation among rheumatoid arthritis patients receiving tofacitinib, tocilizumab, or other biologic treatments. Arthritis Rheumatol. 2016;68:2612–2617.
    1. Vikse J, Henry BM. Tocilizumab in COVID-19: beware the risk of intestinal perforation. Int J Antimicrob Agents. 2020;56:106009.
    1. Rojo M, Cano-Valderrama O, Picazo S, et al. Gastrointestinal perforation after treatment with tocilizumab:an unexpected consequence of COVID-19 pandemic. Am Surgeon. 2020;86:565–566.
    1. Gonzálvez Guardiola P, Díez Ares J, Peris Tomás N, et al. Intestinal perforation in patient with COVID-19 infection treated with tocilizumab and corticosteroids. Report of a clinical case. Cirugia Espanola. 2020;2:156–157.

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