Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 May;6(Suppl 2):e003908.
doi: 10.1136/bmjgh-2020-003908.

Vaccine safety in the next decade: why we need new modes of trust building

Affiliations
Review

Vaccine safety in the next decade: why we need new modes of trust building

Heidi J Larson et al. BMJ Glob Health. 2021 May.

Abstract

Among the realm of highly varied vaccine perceptions and concerns expressed by publics around the world, vaccine safety is the most frequently cited. While many of the safety questions raised have substantial evidence to address the concerns, vaccines do have small risks, and need vigilant and responsive systems to address them. With more and more new vaccines, combinations of vaccines and new technologies to develop and deliver them, new safety concerns will arise that need attention. Adding to this landscape is the dramatic impact which digital communication has had on how fast rumours and vaccine concerns can spread, making the task of the public health and scientific community even more pressing. One of the more recently characterised vaccine safety issues, now named 'immunisation stress-related-response,' has gained particularly high visibility given these highly globally connected social media networks. To better anticipate and address these rapidly shared vaccine safety concerns, a number of global efforts and local responses are being made. Co-created social media campaigns engaging parents and adolescents have been effective, while the WHO's Vaccine Safety Net (VSN) initiative has grown its global network to increase awareness about vaccines and contribute to building confidence in vaccines. The VSN reviews websites around the world to assess their quality and accuracy to ensure and promote access to trustworthy and science-based information on vaccine safety for internet users. These and the efforts of the multiple network partners are more crucial than ever to sustain public confidence in this evolving vaccine safety landscape.

Keywords: immunisation; mental health & psychiatry; vaccines.

PubMed Disclaimer

Conflict of interest statement

Competing interests: HL and CS have research grants from GSK and Merck. HL is on the Vaccine Confidence Advisory Board of Merck.

Figures

Figure 1
Figure 1
Across Africa, confidence in vaccine safety is well below perceived importance.

Similar articles

Cited by

References

    1. Larson HJ, de Figueiredo A, Xiahong Z, et al. . The state of vaccine confidence 2016: global insights through a 67-Country survey. EBioMedicine 2016;12:295–301. 10.1016/j.ebiom.2016.08.042 - DOI - PMC - PubMed
    1. European Centre for Disease Prevention and Control . Rapid literature review on motivating hesitant population groups in Europe to vaccinate. Stockholm: ECDC, 2015. https://ecdc.europa.eu/sites/portal/files/media/en/publications/Publicat...
    1. Karafillakis E, Larson HJ, ADVANCE consortium . The benefit of the doubt or doubts over benefits? A systematic literature review of perceived risks of vaccines in European populations. Vaccine 2017;35:4840–50. 10.1016/j.vaccine.2017.07.061 - DOI - PubMed
    1. Wellcome Trust . Global monitor 2018: how does the world feel about science and health? Available: https://wellcome.ac.uk/sites/default/files/wellcome-globalmonitor-2018.pdf
    1. de Figueiredo A, Simas C, Karafillakis E, et al. . Mapping global trends in vaccine confidence and investigating barriers to vaccine uptake: a large-scale retrospective temporal modelling study. Lancet 2020;396:898–908. 10.1016/S0140-6736(20)31558-0 - DOI - PMC - PubMed

LinkOut - more resources