Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun;69(6):1508-1510.
doi: 10.4103/ijo.IJO_2641_20.

Prolonged face mask use might worsen dry eye symptoms

Affiliations

Prolonged face mask use might worsen dry eye symptoms

Sergio Zaccaria Scalinci et al. Indian J Ophthalmol. 2021 Jun.

Abstract

Purpose: The aim of this study was to explore whether prolonged and consistent face mask use might be associated with worsening of dry eye symptoms in patients with dry eye disease (DED).

Methods: Subjects with a previous diagnosis of DED. Their OSDI scores were compared with those recorded in Fall 2019 using the Wilcoxon paired test. Participants were stratified by face mask use: heavy (Group A) or standard (Group B) face mask users. Heavy use was defined as wearing any type of face mask for at least 6 hours a day, at least 5 days per week in the last 2 months.

Results: 67 subjects (mean age: 45.27 ± 10.06 SD years, 40% males and 60% females). Median OSDI score in Fall 2019: 18.75. Median OSDI in Spring 2020: 20.83. The Hodges-Lehmann median difference was 2.09 (95% CI [1.05, 4.17]) (P < 0.0001). The population was then stratified into heavy and standard face mask users: Group A included heavy users (31 subjects; mean age: 42.81 ± 10.48 SD years; 35% males and 65% females), Group B included standard users (36 subjects; mean age: 47.39 ± 9.31 SD years; 44% males and 56% females). The Hodges-Lehmann median difference was 5.21 (95% CI [3.13, 7.29]) in Group A (P < 0.0001), and 1.04 (95% [0],[ 2.08]) in Group B (P = 0.0177).

Conclusion: Prolonged and consistent face mask use is associated with an increase in OSDI scores. Whether face mask use is responsible for the worsening of symptoms of DED remains to be elucidated.

Keywords: COVID-19; DED; SARS-CoV-19; dry eye disease; face mask; keratoconjunctivitis sicca.

PubMed Disclaimer

Conflict of interest statement

None

Figures

Figure 1
Figure 1
Comparison of OSDI scores of heavy face mask users (Group A) between Fall 2019 and Spring 2020
Figure 2
Figure 2
Comparison of OSDI scores of standard face mask users (Group B) between Fall 2019 and Spring 2020

References

    1. Farrand KF, Fridman M, Stillman IÖ, Schaumberg DA. Prevalence of diagnosed dry eye disease in the United States among adults aged 18 years and older. Am J Ophthalmol. 2017;182:90–8. - PubMed
    1. Lollett IV, Galor A. Dry eye syndrome: Developments and lifitegrast in perspective. Clin Ophthalmol. 2018;12:125–39. - PMC - PubMed
    1. Villatoro AJ, Fernández V, Claros S, Alcoholado C, Cifuentes M, Merayo-Lloves J, et al. Regenerative rherapies in dry eye disease: From growth factors to cell therapy. Int J Mol Sci. 2017;18:2264. - PMC - PubMed
    1. Ziemanski JF, Wolters LR, Jones-Jordan L, Nichols JJ, Nichols KK. Relation between dietary essential fatty acid intake and dry eye disease and meibomian gland dysfunction in postmenopausal women. Am J Ophthalmol. 2018;189:29–40. - PMC - PubMed
    1. Moss SE, Klein R, Klein BE. Prevalence of and risk factors for dry eye syndrome. Arch Ophthalmol. 2000;118:1264–8. - PubMed

LinkOut - more resources