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Case Reports
. 2021 Apr;94(2):252-255.
doi: 10.15386/mpr-1470. Epub 2021 Apr 29.

Pure yolk sac tumor of testis with lung metastasis in an adult patient - case report

Pushpanjali Behera  1 , Arvind Ahuja  1 , Minakshi Bhardwaj  1
Affiliations
Case Reports

Pure yolk sac tumor of testis with lung metastasis in an adult patient - case report

Pushpanjali Behera et al. Med Pharm Rep. 2021 Apr.

Abstract

Pure yolk sac tumor is the most frequently seen testicular tumor in childhood; however it is usually a component of mixed germ cell tumor in adults. Pure yolk sac tumors are quite rare in adults. Pure yolk sac tumor in adults has been categorized as yolk sac tumor, post-pubertal type. We report a case of pure yolk sac tumor of right testis with lung metastasis in a 37-year-old man who was successfully treated by high inguinal orchidectomy and BEP combination chemotherapy.

Keywords: adult; chemotherapy; endodermal sinus tumor; germ cell tumor; metastasis; pure yolk sac tumor.

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Figures

Figure 1. A–C
Figure 1. A–C
A- CECT image showing an infiltrating heterogenous enhancing mass lesion in the right testis; B- CECT lung showing metastatic solitary nodule in left upper lobe; C- Gross of orchidectomy specimen showing grey white tumor along with areas of hemorrhage (red arrow) and necrosis (black arrow).
Figure 2. A–F
Figure 2. A–F
Photomicrograph of tumor. A- endodermal sinus pattern [H&E, 200X]; B- Schiller Duval body (yellow arrows) [H&E, 400X]; C- solid sheet; D- PAS positive hyaline globules (yellow arrows) [H&E, 400X]; E and F- Tumor cell were focally immunoreactive for AFP [E] and revealed diffuse Pan-CK [F] positivity [IHC, 400X].
See this image and copyright information in PMC

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