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. 2021 Oct;57(10):1612-1616.
doi: 10.1111/jpc.15568. Epub 2021 May 20.

Neuropsychological assessment of paediatric brain tumour survivors: Factors associated with assessment

Rebecca F Slykerman  1 , Emily Jenner  1 , Karen Tsui  2 , Stephen Laughton  2
Affiliations

Neuropsychological assessment of paediatric brain tumour survivors: Factors associated with assessment

Rebecca F Slykerman et al. J Paediatr Child Health. 2021 Oct.

Abstract

Aim: Paediatric brain tumour survivors are at increased risk of neurocognitive deficits that affect their education. The aim of this study was to assess the proportion of brain tumour survivors who historically received a neuropsychological assessment and examine the demographic and treatment-related variables associated with neuropsychological assessment. A further aim was to determine the number and treatment profile of brain tumour survivors who would benefit from neuropsychological assessment.

Methods: Data from the New Zealand Children's Cancer Registry including treatments received, was used to identify children treated for a brain tumour at Starship Children's Hospital between January 2009 and December 2015. Clinical records were examined for evidence of a neuropsychological assessment in the form of a written report. Logistic regression models were used to determine factors associated with receipt of an assessment.

Results: Of the 132 brain tumour survivors, 37 (28.0%) had evidence of a neuropsychological assessment in their clinical records. In adjusted analysis, children who were treated with all three of surgery, chemotherapy and radiotherapy (n = 38) were more likely to have had an assessment (odds ratio: 12.90; 95% confidence interval: 4.76-34.93) than children who had either no treatment, chemotherapy alone, surgery alone or chemotherapy and surgery (n = 73). Treatment with radiotherapy alone or with either chemotherapy or surgery (n = 21) was not significantly associated with receipt of assessment (odds ratio = 2.40; 95% confidence interval: 0.69-8.37).

Conclusions: It is important to identify the number of children who might benefit from neuropsychological assessment to inform prioritisation within existing resource and plan for additional resource if required. With a focus on reducing late effects, it is imperative that neuropsychological assessment is an integral component of a paediatric brain tumour programme.

Keywords: brain tumour; late effects; neuropsychological assessment.

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