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Review
. 2022 Mar;269(3):1209-1224.
doi: 10.1007/s00415-021-10608-4. Epub 2021 May 20.

Digital therapeutics in neurology

G Abbadessa  1 , F Brigo  2 , M Clerico  3 , S De Mercanti  3 , F Trojsi  1 , G Tedeschi  1 , S Bonavita #  1 , L Lavorgna #  4
Affiliations
Review

Digital therapeutics in neurology

G Abbadessa et al. J Neurol. 2022 Mar.

Abstract

Digital therapeutics (DTx) is a section of digital health defined by the DTx Alliance as "delivering evidence-based therapeutic interventions to patients that are driven by software to prevent, manage, or treat a medical disorder or disease. They are used independently or in concert with medications, devices, or other therapies to optimize patient care and health outcomes". Chronic disabling diseases could greatly benefit from DTx. In this narrative review, we provide an overview of DTx in the care of patients with neurological dysfunctions.

Keywords: Digital therapeutics; Exergames; Neurological disorders; Rehabilitation; Validation studies.

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Conflict of interest statement

The authors declare that there is no conflict of interest regarding the publication of this article.

References

    1. WHO guideline Recommendations on Digital Interventions for Health System Strengthening. Geneva: World Health Organization; 2019. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541905/ - PubMed
    1. Lavorgna L, Brigo F, Moccia M, et al. e-Health and multiple sclerosis: an update. Mult Scler. 2018;24(13):1657–1664. - PubMed
    1. https://wwwdtxalliance.org/
    1. Khirasaria R, Singh V, Batta A. Exploring digital therapeutics: the next paradigm of modern health-care industry. Perspect Clin Res. 2020;11(2):54–58. - PMC - PubMed
    1. Yekutiel M, Guttman E. A controlled trial of the retraining of the sensory function of the hand in stroke patients. J Neurol Neurosurg Psychiatry. 1993;56(3):241–244. - PMC - PubMed