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doi: 10.1016/j.molcel.2021.04.020.
More writing: mTORC1 promotes m6A mRNA methylation
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- PMID: 34019785
- DOI: 10.1016/j.molcel.2021.04.020
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More writing: mTORC1 promotes m6A mRNA methylation
Mol Cell.
.
Free article
Abstract
Cho et al. (2021) and Villa et al. (2021) demonstrate that mTORC1 stimulates m6A mRNA methylation via WTAP expression and SAM synthesis. Increased mRNA methylation in turn promotes cell growth by enhancing mRNA degradation or translation.
Copyright © 2021 Elsevier Inc. All rights reserved.
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mTORC1 promotes cell growth via m6A-dependent mRNA degradation.Mol Cell. 2021 May 20;81(10):2064-2075.e8. doi: 10.1016/j.molcel.2021.03.010. Epub 2021 Mar 22. Mol Cell. 2021. PMID: 33756105 Free PMC article.
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mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis.Mol Cell. 2021 May 20;81(10):2076-2093.e9. doi: 10.1016/j.molcel.2021.03.009. Epub 2021 Mar 22. Mol Cell. 2021. PMID: 33756106 Free PMC article.
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