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. 2021 May 22;21(1):252.
doi: 10.1186/s12872-021-02065-8.

Impact of diurnal temperature range on cardiovascular disease hospital admissions among Chinese farmers in Dingxi (the Northwest China)

Guangyu Zhai  1   2 , Jintao Qi  3 , Guorong Chai  2
Affiliations

Impact of diurnal temperature range on cardiovascular disease hospital admissions among Chinese farmers in Dingxi (the Northwest China)

Guangyu Zhai et al. BMC Cardiovasc Disord. .

Abstract

Background: Diurnal temperature range (DTR) has been widely applied in exploring its effect on cardiovascular disease (CVD). However, few studies have investigated the correlations between DTR and CVD in poor rural areas in China. This study aimed to examine the association between DTR and CVD in rural China.

Methods: A distributed lag nonlinear model was used to evaluate the relationship between DTR and CVD risk among farmers living in the city of Dingxi (Northwest China) in the period from January 1, 2016 to December 31, 2019.

Results: We observed nonlinear M-patterns between the relative risk (RR) of DTR (reference: median DTR, 12 °C) and CVD hospitalizations in all subgroups. The peak RR of CVD was noticed at DTR of 6 °C (total: 1.418; men: 1.546; women: 1.403; young: 1.778; old: 2.549) and 17 °C (total: 1.781; men: 1.937; women: 1.712; young: 2.233; old: 1.798). The adverse effect of DTR on CVD risk was more pronounced in females (RR 1.438) and elderly (RR 2.034) than males (RR 1.141) and younger adults (RR 1.852) at the extremely low (5th, 4 °C) DTR. The reverse was observed at the extremely high DTR (95th, 19 °C) (male: 1.267; females: 0.993; young: 1.586; old: 1.212).

Conclusions: DTR is associated with CVD morbidity. This association was more pronounced in women and elderly, but men and younger peoples at extremely high DTR (19 °C). Future measures should take DTR into account to prevent CVD among susceptible populations.

Keywords: Cardiovascular diseases; Distributed lag nonlinear model; Diurnal temperature range; Poverty area.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Proportion of agricultural population in Dingxi and major cities in China
Fig. 2
Fig. 2
The cumulative lag effects of DTR on CVD’ RR for subgroups. Reference DTR: 12 °C. Lag for 0–21 day
Fig. 3
Fig. 3
title: Estimated cumulative lag effect of extreme DTR on RR of CVD. Reference DTR: 12 °C. Lag for 0–21 day
Fig. 4
Fig. 4
Cumulative effect of DTR on RR of CVD at six different types of lags
Fig. 5
Fig. 5
Three-dimensional plot of the relationship between DTR and CVD hospital admission over 21 lag days
See this image and copyright information in PMC

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