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Review
. 2021 Jun;50(2):287-297.
doi: 10.1016/j.ecl.2021.03.006. Epub 2021 Apr 28.

Diabetes and Osteoporosis: Part II, Clinical Management

G Isanne Schacter  1 , William D Leslie  2
Affiliations
Review

Diabetes and Osteoporosis: Part II, Clinical Management

G Isanne Schacter et al. Endocrinol Metab Clin North Am. 2021 Jun.

Abstract

Diabetes-induced osteoporosis is characterized by an increase in fracture risk. FRAX, the most widely used tool, underestimates the risk of fracture in both type 1 and type 2 diabetes. Specific adjustments to FRAX can help to better identify patients with diabetes at increased risk of fracture and select those at high fracture risk for treatment. Although clinical trial data are limited, the available evidence indicates that the presence of diabetes does not alter antiosteoporotic treatment response in patients with diabetes.

Keywords: Bone; Bone mineral density; Diabetes; Dual-energy x-ray absorptiometry; Fracture; Osteoporosis.

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