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Editorial
. 2021 Sep;78(3):335-337.
doi: 10.1053/j.ajkd.2021.03.016. Epub 2021 May 20.

Tubular Kidney Biomarker Insights Through Factor Analysis

Carl P Walther  1 , Julia S Benoit  2
Affiliations
Editorial

Tubular Kidney Biomarker Insights Through Factor Analysis

Carl P Walther et al. Am J Kidney Dis. 2021 Sep.
No abstract available

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Conflict of interest statement

Financial Disclosure: The authors declare that they have no relevant financial interests.

Figures

Figure 1.
Figure 1.. Steps involved in the factor derivation, interpretation, and evaluation.
Notes: The factor rotations used an oblique technique (Promax), so factors were not orthogonal, but are represented as such in panel 1 for easier visualization. Values of factor loadings (which we graph in panel 1) were obtained from supplementary material from a prior publication by the same group; biomarker names in gray have small factor loadings. The x and y axes in panel 1 are labeled with the factor names (for interpretability), although the names would not be applied until the step represented in panel 2. Abbreviations: α1m, α−1 microglobulin, β2m; β−2 microglobulin; IL18, interleukin-18; KIM1, kidney injury molecule-1; NGAL, neutrophil gelatinase associated lipocalin; YKL-40, chitinase-3-like protein; MCP-1, monocyte chemoattractant protein-1; UMOD, uromodulin; min. met., mineral metabolism; inj./fib., injury/fibrosis; inj./rep., injury/repair; res./min.met., reserve/mineral metabolism.
See this image and copyright information in PMC

Comment on

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