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Review
. 2021 May;45(3):363-370.
doi: 10.1016/j.jgr.2020.08.004. Epub 2020 Sep 1.

The regulatory role of Korean ginseng in skin cells

Long You  1 , Jae Youl Cho  1   2
Affiliations
Review

The regulatory role of Korean ginseng in skin cells

Long You et al. J Ginseng Res. 2021 May.

Abstract

As the largest organ in our body, the skin acts as a barrier against external stress and damages. There are various cell types of skin, such as keratinocytes, melanocytes, fibroblasts, and skin stem cells. Korean ginseng, which is one of the biggest distributions of ginseng worldwide, is processed into different products, such as functional food, cosmetics, and medical supplies. This review aims to introduce the functional role of Korean ginseng on different dermal cell types, including the impact of Korean ginseng in anti-photodamaging, anti-inflammatory, anti-oxidative, anti-melanogenic, and wound healing activities, etc. We propose that this information could form the basis of future research of ginseng-derived components in skin health.

Keywords: Fibroblasts; Keratinocytes; Korean ginseng; Melanocytes; Skin health.

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Conflict of interest statement

The authors declare that no conflicts of interest exist.

Figures

Fig. 1
Fig. 1
The structures of ginseng-derived components.
Fig. 2
Fig. 2
The role of Korean ginseng in skin keratinocytes, melanocytes and fibroblasts. A. Schematic structure of skin. B, C and D. Functional role of ginseng-derived components in B. keratinocytes, C. melanocytes, and D. fibroblasts.
See this image and copyright information in PMC

References

    1. Gould J. Superpowered skin. Nature. 2018;563:S84–S85. - PubMed
    1. Gravitz L. Skin. Nature. 2018;563:S83. - PubMed
    1. Hoerter J.D., Bradley P., Casillas A., Chambers D., Denholm C., Johnson K., Weiswasser B. Extrafollicular dermal melanocyte stem cells and melanoma. Stem Cells Int. 2012;2012:407079. - PMC - PubMed
    1. Ortonne J.P. Normal and abnormal skin color. Ann Dermatol Venereol. 2012;139:S125–S129. - PubMed
    1. Nilforoushzadeh M.A., Ashtiani H.R.A., Jaffary F., Jahangiri F., Nikkhah N., Mahmoudbeyk M., Fard M., Ansari Z., Zare S. Dermal fibroblast cells: biology and function in skin regeneration. J Ski Stem Cell. 2017;4

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