Getting Excited Through Cyclin: A Role for Endothelial Cdk5 Signaling in Hippocampal Hyperexcitability

Comment

Alisha Aroor et al. Epilepsy Curr. 2020.

. 2020 Oct 12;20(6):396-398.

doi: 10.1177/1535759720958418. eCollection 2020 Nov-Dec.

No abstract available

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Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis.
Liu XX, Yang L, Shao LX, He Y, Wu G, Bao YH, Lu NN, Gong DM, Lu YP, Cui TT, Sun NH, Chen DY, Shi WX, Fukunaga K, Chen HS, Chen Z, Han F, Lu YM. Liu XX, et al. J Exp Med. 2020 Jan 6;217(1):e20180992. doi: 10.1084/jem.20180992. J Exp Med. 2020. PMID: 31699822 Free PMC article.

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