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Multicenter Study
. 2021 May 5:12:608575.
doi: 10.3389/fendo.2021.608575. eCollection 2021.

A Researcher's Guide to the Measurement and Modeling of Puberty in the ABCD Study® at Baseline

Theresa W Cheng  1 , Lucía Magis-Weinberg  2 , Victoria Guazzelli Williamson  1 , Cecile D Ladouceur  3 , Sarah L Whittle  4 , Megan M Herting  5 , Kristina A Uban  6 , Michelle L Byrne  1   7 , Marjolein E A Barendse  1 , Elizabeth A Shirtcliff  8 , Jennifer H Pfeifer  1
Affiliations
Multicenter Study

A Researcher's Guide to the Measurement and Modeling of Puberty in the ABCD Study® at Baseline

Theresa W Cheng et al. Front Endocrinol (Lausanne). .

Abstract

The Adolescent Brain Cognitive Development℠ (ABCD) Study is an ongoing, diverse, longitudinal, and multi-site study of 11,880 adolescents in the United States. The ABCD Study provides open access to data about pubertal development at a large scale, and this article is a researcher's guide that both describes its pubertal variables and outlines recommendations for use. These considerations are contextualized with reference to cross-sectional empirical analyses of pubertal measures within the baseline ABCD dataset by Herting, Uban, and colleagues (2021). We discuss strategies to capitalize on strengths, mitigate weaknesses, and appropriately interpret study limitations for researchers using pubertal variables within the ABCD dataset, with the aim of building toward a robust science of adolescent development.

Keywords: DHEA; adolescent brain cognitive development study; estradiol; puberty; salivary hormones; testosterone.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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